SCEC research labs are using non-destructive bioanalytical techniques like dielectrophoresis, mass spectroscopy and potentiometry to assess the state of the cell in one environment verses another. These techniques are used to measure cell phenotype, specifically cell density, scattering properties, impedance, secretions, metabolomics and mechanical properties.
The SCEC labs using bioanalytical techniques to study cell phenotypes include:
The Curtis Laboratory is characterizing supermolecular aggregates and networks formed by protein-HA interactions using a variety of techniques, including microrheology, Fluorescence Recovery after Photobleaching (FRAP) and light scattering.
The Lu Laboratory is engineering Bio Micro-Electro-Mechanical Systems (BioMEMS) and microfluidic devices to study the fundamental biological questions in neuroscience, cell biology, and biotechnology.
The Santangelo Laboratory is studying infectious disease, molecular imaging, nano-biophotonics, and optical microscopy.
The Precision Biosystems Laboratory is combining optics, MEMs, signal processing, machine design, molecular biology, and novel manufacturing techniques to develop innovative tools for biomedical research and clinical applications.
The Platt Laboratory is fusing the quantitative analysis of cell biology, physiology, and engineering principles to understand how cells sense, respond, and remodel their immediate environments for repair and regeneration.